Gene
tinf2
- ID
- ZDB-GENE-030131-6168
- Name
- TERF1 (TRF1)-interacting nuclear factor 2
- Symbol
- tinf2 Nomenclature History
- Previous Names
-
- TIN2 (1)
- wu:fi37c10
- zgc:158289
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have telomeric DNA binding activity. Predicted to be involved in regulation of telomere maintenance via telomere lengthening and telomere capping. Predicted to localize to shelterin complex. Human ortholog(s) of this gene implicated in Revesz syndrome and autosomal dominant dyskeratosis congenita 3. Is expressed in several structures, including gill; heart; liver; pleuroperitoneal region; and post-vent region. Orthologous to human TINF2 (TERF1 interacting nuclear factor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant dyskeratosis congenita 3 | Alliance | Dyskeratosis congenita, autosomal dominant 3 | 613990 |
| Revesz syndrome | Alliance | Revesz syndrome | 268130 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | TERF1-interacting nuclear factor 2 | TERF1-interacting nuclear factor 2, N-terminal domain |
|---|---|---|---|
|
UniProtKB:F1R9M2
|
585 | ||
|
UniProtKB:A0A8M3AU25
|
566 |
Interactions and Pathways
No data available
Plasmids
No data available