Gene
insig1
- ID
- ZDB-GENE-030131-6121
- Name
- insulin induced gene 1
- Symbol
- insig1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable oxysterol binding activity. Predicted to be involved in several processes, including SREBP signaling pathway; SREBP-SCAP complex retention in endoplasmic reticulum; and cellular response to insulin stimulus. Predicted to act upstream of or within cholesterol metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of SREBP-SCAP-Insig complex. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including anterior axial hypoblast; immature eye; liver; notochord; and yolk syncytial layer. Orthologous to human INSIG1 (insulin induced gene 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55439 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR025929 | Insulin-induced protein family |
Domain Details Per Protein
| Protein | Length | Insulin-induced protein family |
|---|---|---|
|
UniProtKB:Q8AV61
|
251 | |
|
UniProtKB:B2GRG1
|
251 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
insig1-201
(1)
|
Ensembl | 3,325 nt | ||
| mRNA |
insig1-203
(1)
|
Ensembl | 827 nt | ||
| ncRNA |
insig1-003
(1)
|
Ensembl | 1,103 nt |
Interactions and Pathways
No data available
Plasmids
No data available