Gene
hgs
- ID
- ZDB-GENE-030131-6107
- Name
- hepatocyte growth factor-regulated tyrosine kinase substrate
- Symbol
- hgs Nomenclature History
- Previous Names
-
- fi34f05
- wu:fi34f05
- zgc:63492 (1)
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable ubiquitin binding activity. Predicted to be involved in endocytic recycling and receptor internalization. Predicted to act upstream of or within phosphorylation. Predicted to be located in early endosome membrane. Predicted to be active in early endosome. Orthologous to human HGS (hepatocyte growth factor-regulated tyrosine kinase substrate).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63492 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003903 | Ubiquitin interacting motif |
| Domain | IPR000306 | FYVE zinc finger |
| Domain | IPR002014 | VHS domain |
| Domain | IPR017455 | Zinc finger, FYVE-related |
| Domain | IPR024641 | Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain |
| Family | IPR017073 | Hepatocyte growth factor-regulated tyrosine kinase substrate/VPS27 |
| Homologous_superfamily | IPR008942 | ENTH/VHS |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Domain Details Per Protein
| Protein | Length | ENTH/VHS | FYVE zinc finger | Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain | Hepatocyte growth factor-regulated tyrosine kinase substrate/VPS27 | Ubiquitin interacting motif | VHS domain | Zinc finger, FYVE/PHD-type | Zinc finger, FYVE-related | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PSI2
|
776 | |||||||||
|
UniProtKB:A0A8M2BBJ6
|
773 | |||||||||
|
UniProtKB:A0A8M9PK93
|
771 | |||||||||
|
UniProtKB:A0A8M9PSI7
|
768 | |||||||||
|
UniProtKB:E9QCS7
|
757 | |||||||||
|
UniProtKB:A0A8M9PW14
|
761 | |||||||||
|
UniProtKB:A0A8M9PEL3
|
767 | |||||||||
|
UniProtKB:A0A8M9P4S8
|
762 | |||||||||
|
UniProtKB:A0A8M9PVZ9
|
777 |
Interactions and Pathways
No data available
Plasmids
No data available