Gene
e2f6
- ID
- ZDB-GENE-030131-513
- Name
- E2F transcription factor 6
- Symbol
- e2f6 Nomenclature History
- Previous Names
-
- fb34f06
- si:ch211-195d17.2
- THAP-E2F6 fusion gene (1)
- wu:fb34f06
- zgc:136607
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific; sequence-specific DNA binding activity; and transcription factor binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; and regulation of cell cycle. Predicted to localize to RNA polymerase II transcription factor complex.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu1069 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
| Domain | IPR006612 | THAP-type zinc finger |
| Domain | IPR032198 | E2F transcription factor, CC-MB domain |
| Family | IPR015633 | E2F Family |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
| Homologous_superfamily | IPR037241 | E2F-DP heterodimerization region |
| Homologous_superfamily | IPR038441 | THAP-type zinc finger superfamily |
Domain Details Per Protein
| Protein | Length | E2F/DP family, winged-helix DNA-binding domain | E2F-DP heterodimerization region | E2F Family | E2F transcription factor, CC-MB domain | THAP-type zinc finger | THAP-type zinc finger superfamily | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q5TZC4
|
406 | ||||||||
|
UniProtKB:A0A8M1N779
|
405 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:ch211-195d17.2-201
(1)
|
Ensembl | 1,580 nt | ||
| mRNA |
si:ch211-195d17.2-202
(1)
|
Ensembl | 1,412 nt | ||
| mRNA |
si:ch211-195d17.2-203
(1)
|
Ensembl | 1,583 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance