ZFIN ID: ZDB-GENE-030131-4827
Gene Name: hedgehog interacting protein
Gene Symbol: hhip
Previous Names: Hip (1), uki, fd99f01, ukkie, wu:fc52e12, wu:fd99f01, zgc:153478
Location: Chr: 1   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 6 figures from 3 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  adaxial cell, adductor mandibulae, anterior macula, axis (all 32) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 10 genotypes
Alleles: hu418b, hu540a, tc256d
Knockdown reagents: MO1-hhip (1), MO2-hhip (1), MO3-hhip (1)
PHENOTYPE
Data: 13 figures from 6 publications
Observed in: anal fin, anatomical system, caudal fin, cell proliferation (all 26) expand
GENE ONTOLOGY
Ontology GO Term
Biological Process negative regulation of muscle organ development (more)
Cellular Component intrinsic component of plasma membrane (more)
Molecular Function catalytic activity (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000742 (1)
  • InterPro:IPR011041 (1)
  • InterPro:IPR011042 (1)
  • InterPro:IPR012938 (1)
  • InterPro:IPR013032 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS01186 (1)
  • PROSITE:PS50026 (1)
  • Pfam:PF07995 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA hhip-001 (1) 4575
    ncRNA hhip-002 (1) 731
    GENE PRODUCT DESCRIPTION No description available
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hhip No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    hhip Contained in: [BAC] CH211-194G2 (1) (order this)
    hhip Contains: [SNP] rs3727539 (1)
    hhip Encodes: [EST] fc52e12, fd99f01
    [cDNA] MGC:153478 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001080012 (1) 4587 bp
    Genomic GenBank:BX276105 (1) 209486 bp Blast at MegaBLAST
    Polypeptide UniProtKB:A1A5I0 (1) 693 aa
    Sequence Clusters UniGene:119698 (1)
    Sequence Information (all 15)
    OTHER hhip GENE PAGES
  • Gene:326102 (1)
  • VEGA:OTTDARG00000027132 (1)
  • Ensembl(Zv9):ENSDARG00000060397 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA NT CL
    Zebrafish hhip 1  
    Human HHIP 4 (4q28-q32)
  • OMIM:606178
  • Gene:64399
  • Mouse Hhip 8 ( 37.95 cM)
  • MGI:1341847
  • Gene:15245
  • Orthology Details
    CITATIONS (37)