Gene

pdss1

ID

ZDB-GENE-030131-4430

Name

prenyl (decaprenyl) diphosphate synthase, subunit 1

Symbol

pdss1 Nomenclature History

Previous Names

tprt (1)
wu:fc11f12
wu:fd05d05
zgc:112058

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Description

Predicted to have transferase activity. Predicted to be involved in isoprenoid biosynthetic process. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 2. Is expressed in several structures, including alar plate midbrain region; lens placode; musculature system; optic vesicle; and segmental plate. Orthologous to human PDSS1 (decaprenyl diphosphate synthase subunit 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:112058 (16 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pdss1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
primary coenzyme Q10 deficiency 2	Alliance	Coenzyme Q10 deficiency, primary, 2	614651

Associated With pdss1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR033749	Polyprenyl synthetase, conserved site
Family	IPR000092	Polyprenyl synthetase
Homologous_superfamily	IPR008949	Isoprenoid synthase domain superfamily