Gene
tmem260
- ID
- ZDB-GENE-030131-4198
- Name
- transmembrane protein 260
- Symbol
- tmem260 Nomenclature History
- Previous Names
-
- fc80c01
- wu:fc80c01
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable dolichyl-phosphate-mannose-protein mannosyltransferase activity. Acts upstream of or within central nervous system development. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in T-cell non-Hodgkin lymphoma; non-Hodgkin lymphoma; and stomach cancer. Orthologous to human TMEM260 (transmembrane protein 260).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Ta-Shma et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Structural heart defects and renal anomalies syndrome | 617478 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Glycosyltransferase 117 domain-containing protein | Protein O-mannosyl-transferase TMEM260-like |
|---|---|---|---|
|
UniProtKB:A0A8M3AUJ3
|
652 | ||
|
UniProtKB:A0A8M9PLK5
|
683 | ||
|
UniProtKB:E7F5M2
|
684 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tmem260-201
(1)
|
Ensembl | 3,526 nt | ||
| mRNA |
tmem260-202
(1)
|
Ensembl | 6,333 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance