ZFIN ID: ZDB-GENE-030131-4120
Gene Name: lysine (K)-specific methyltransferase 2E
Gene Symbol: kmt2e
Previous Names: mll5, wu:fc74b02, zgc:64223
Location: Chr: 4   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:64223]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
  central nervous system, intermediate cell mass of mesoderm, unspecified
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa13142
Knockdown reagents: MO1-kmt2e (1)
PHENOTYPE No data available
GENE ONTOLOGY
Ontology GO Term
Molecular Function metal ion binding (more)
GO Terms (all 2)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001214 (1)
  • InterPro:IPR001965 (1)
  • InterPro:IPR011011 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR019786 (1)
  • InterPro:IPR019787 (1)
  • PROSITE:PS01359 (1)
  • PROSITE:PS50016 (1)
  • PROSITE:PS50280 (1)
  • Pfam:PF00628 (1)
  • Pfam:PF00856 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA kmt2e-001 (1) 4168
    kmt2e-002 (1) 2704
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM kmt2e No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    kmt2e Contained in: [BAC] DKEY-9A20 (1), DKEY-63J13 (1), DKEY-105O6 (1)
    kmt2e Encodes: [EST] fc74b02
    [cDNA] MGC:64223 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_199717 (1) 2608 bp
    Genomic GenBank:BX537162 (1) 223816 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q5TZ08 (1) 1265 aa
    Sequence Clusters UniGene:79417 (1)
    Sequence Information (all 45)
    OTHER kmt2e GENE PAGES
  • Gene:325395 (1)
  • VEGA:OTTDARG00000008335 (1)
  • Ensembl(Zv9):ENSDARG00000007523 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish kmt2e 4  
    Human KMT2E 7 (7q22.1)
  • OMIM:608444
  • Gene:55904
  • Orthology Details
    CITATIONS (18)