Gene
hmga2
- ID
- ZDB-GENE-030131-3148
- Name
- high mobility group AT-hook 2
- Symbol
- hmga2 Nomenclature History
- Previous Names
-
- wu:fc27f12
- wu:fc28f02
- wu:fc57d12
- zgc:77719
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have DNA-(apurinic or apyrimidinic site) endonuclease activity. Predicted to be involved in base-excision repair and regulation of transcription, DNA-templated. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in leiomyoma; lipoma; ovarian cancer; and uterine fibroid. Is expressed in several structures, including cardiovascular system; head; nervous system; pectoral fin bud; and pronephric duct. Orthologous to human HMGA2 (high mobility group AT-hook 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77719 (17 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Wang et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Silver-Russell syndrome 5 | 618908 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | AT hook, DNA-binding motif | High mobility group protein HMGA | HMG-I/HMG-Y, DNA-binding, conserved site |
|---|---|---|---|---|
|
UniProtKB:Q6P038
|
110 |
Interactions and Pathways
No data available
Plasmids
No data available