Gene
farp2
- ID
- ZDB-GENE-030131-2993
- Name
- FERM, RhoGEF and pleckstrin domain protein 2
- Symbol
- farp2 Nomenclature History
- Previous Names
-
- wu:fc23d05
- wu:fp25d09
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have Rac guanyl-nucleotide exchange factor activity. Predicted to localize to cytoskeleton. Orthologous to human FARP2 (FERM, ARH/RhoGEF and pleckstrin domain protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019747 | FERM conserved site |
| Domain | IPR000219 | Dbl homology (DH) domain |
| Domain | IPR000299 | FERM domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR014847 | FERM adjacent |
| Domain | IPR018979 | FERM, N-terminal |
| Domain | IPR018980 | FERM, C-terminal PH-like domain |
| Domain | IPR019748 | FERM central domain |
| Domain | IPR019749 | Band 4.1 domain |
| Domain | IPR041788 | FARP1/FARP2/FRMD7, FERM domain C-lobe |
| Family | IPR000798 | Ezrin/radixin/moesin-like |
| Family | IPR051835 | RAC1-specific guanine nucleotide exchange factor |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR014352 | FERM/acyl-CoA-binding protein superfamily |
| Homologous_superfamily | IPR029071 | Ubiquitin-like domain superfamily |
| Homologous_superfamily | IPR035899 | Dbl homology (DH) domain superfamily |
| Homologous_superfamily | IPR035963 | FERM superfamily, second domain |
Domain Details Per Protein
| Protein | Length | Band 4.1 domain | Dbl homology (DH) domain | Dbl homology (DH) domain superfamily | Ezrin/radixin/moesin-like | FARP1/FARP2/FRMD7, FERM domain C-lobe | FERM/acyl-CoA-binding protein superfamily | FERM adjacent | FERM central domain | FERM conserved site | FERM, C-terminal PH-like domain | FERM domain | FERM, N-terminal | FERM superfamily, second domain | PH-like domain superfamily | Pleckstrin homology domain | RAC1-specific guanine nucleotide exchange factor | Ubiquitin-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PMS8
|
1043 | |||||||||||||||||
|
UniProtKB:A0A8M9Q0H0
|
1036 | |||||||||||||||||
|
UniProtKB:E7FE33
|
1044 | |||||||||||||||||
|
UniProtKB:A0A8M9Q6T8
|
978 | |||||||||||||||||
|
UniProtKB:A0A8M3ATD1
|
1051 |
Interactions and Pathways
No data available
Plasmids
No data available