| ZFIN ID: ZDB-GENE-030131-2921 |
| Gene Name: | dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) |
|---|---|
| Gene Symbol: | dlat |
| Previous Names: | noa, fc86g11, fj57d06, no optokinetic nystagmus a, no optokinetic response b (1), nrb (1), wu:fc14f10 (1), wu:fc21f08 (1), wu:fc86g11 (1), wu:fj57d06 (1) |
| Nomenclature History | |
| All Expression Data: | 2 figures from Baxendale et al., 2009 |
| Wild-type Stages, Structures: | Segmentation:10-13 somites (14.0h-16.0h) to Pharyngula:Prim-5 (24.0h-30.0h) |
|---|---|
| adaxial cell, myotome | |
| Curated Microarray Expression: | GEO (1) |
| Mutant lines: | 4 genotypes |
| Alleles: | a13, m631 |
| Data: | 2 figures from Phenotype Annotation (1994-2006) |
| Observed in: |
eye,
musculoskeletal movement,
pigment cell,
sensory system
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| Phenotype of Human Orthologue | OMIM Phenotype ID |
|---|---|
| Pyruvate dehydrogenase E2 deficiency | 245348 |
| Ontology | GO Term |
|---|---|
| Biological Process | acetyl-CoA biosynthetic process from pyruvate (more) |
| Cellular Component | pyruvate dehydrogenase complex (more) |
| Molecular Function | CONTRIBUTES_TO pyruvate dehydrogenase activity (more) |
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| Type | Name | Length (bp) | Analysis | |||
|---|---|---|---|---|---|---|
| mRNA | dlat-001 (1) | 2072 |
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 Withdrawn Transcripts |
| dlat Contained in: | [BAC] CH73-285B21 (1) (order this), DKEYP-14B8 (1) |
| dlat Contains: | [SNP] rs3729104 (1), rs3729105 (1) |
| dlat Encodes: |
[EST]
fc14f10,
fc21f08,
fc86g11,
fj57d06
[cDNA] MGC:194568 (1) (order this), MGC:194582 (1) (order this) |
| dlat Has Artifact: | [cDNA] MGC:111854 (1) (order this) |
| Type | Accession # | Length (bp/aa) | Analysis |
|---|---|---|---|
| RNA | RefSeq:NM_212667 (1) | 1959 bp |
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| Genomic | GenBank:BX296544 (1) | 168838 bp | |
| Polypeptide | UniProtKB:Q804C3 (1) | 652 aa |
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| Sequence Clusters | UniGene:31625 (1) |
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| Chr: 21 Details | View Map: Merged Individual Panels |
| Evidence | ||||||
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| Species | Symbol | Chromosome (Position) | Accession # | AA | CL | |
| Zebrafish | dlat | 21 |
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| Human | DLAT | 11 (11q23.1) |
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