Gene
shc1
- ID
- ZDB-GENE-030131-2538
- Name
- SHC (Src homology 2 domain containing) transforming protein 1
- Symbol
- shc1 Nomenclature History
- Previous Names
-
- si:dkey-246i14.4
- wu:fc10h03 (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have receptor tyrosine kinase binding activity. Involved in angiogenesis. Predicted to localize to plasma membrane. Orthologous to human SHC1 (SHC adaptor protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Sweet et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000980 | SH2 domain |
| Domain | IPR006019 | Phosphotyrosine interaction domain, Shc-like |
| Domain | IPR006020 | PTB/PI domain |
| Domain | IPR035676 | SH2 adaptor protein C, SH2 domain |
| Family | IPR051235 | Centrosomal Protein 152/SHC-Transforming Protein |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR036860 | SH2 domain superfamily |
Domain Details Per Protein
| Protein | Length | Centrosomal Protein 152/SHC-Transforming Protein | PH-like domain superfamily | Phosphotyrosine interaction domain, Shc-like | PTB/PI domain | SH2 adaptor protein C, SH2 domain | SH2 domain | SH2 domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M6Z1Z9
|
593 | |||||||
|
UniProtKB:E9QCZ8
|
449 | |||||||
|
UniProtKB:E7F3T0
|
454 | |||||||
|
UniProtKB:A0A8M3AJ37
|
575 |
Interactions and Pathways
No data available
Plasmids
No data available