Gene
plekhg6
- ID
- ZDB-GENE-030131-2517
- Name
- pleckstrin homology domain containing, family G (with RhoGef domain) member 6
- Symbol
- plekhg6 Nomenclature History
- Previous Names
-
- fc10d07
- si:ch211-215m13.2
- wu:fc10d07 (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have guanyl-nucleotide exchange factor activity. Orthologous to human PLEKHG6 (pleckstrin homology and RhoGEF domain containing G6).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Allele | Type | Localization | Consequence | Mutagen | Supplier |
---|---|---|---|---|---|
sa11583 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000219 | Dbl homology (DH) domain |
Domain | IPR001849 | Pleckstrin homology domain |
Family | IPR040181 | Pleckstrin homology domain-containing family G member 5/7 |
Homologous_superfamily | IPR011993 | PH-like domain superfamily |
Homologous_superfamily | IPR035899 | Dbl homology (DH) domain superfamily |
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Domain Details Per Protein
Protein | Length | Dbl homology (DH) domain | Dbl homology (DH) domain superfamily | PH-like domain superfamily | Pleckstrin homology domain | Pleckstrin homology domain-containing family G member 5/7 |
---|---|---|---|---|---|---|
UniProtKB:A0A8M3AHZ2
|
977 | |||||
UniProtKB:A0A8M3ATA9
|
1025 | |||||
UniProtKB:A0A140LH23
|
1024 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
plekhg6-201
(1)
|
Ensembl | 3,643 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH211-215M13 | ZFIN Curated Data | |
Encodes | EST | fc10d07 |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:XM_009292201 (1) | 3577 nt | ||
Genomic | GenBank:CR533575 (1) | 115032 nt | ||
Polypeptide | UniProtKB:A0A8M3ATA9 (1) | 1025 aa |
- Cao, M., Wang, N., Yan, X., Yang, N., Fu, Q., Zhang, X., Zhang, Y., Li, C. (2022) Structures, evolutionary relationships and expression profiles of the tumour necrosis factor superfamily and their receptors in black rockfish (Sebastes schlegelii). Developmental and comparative immunology. 132:104405
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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