Gene
cfhl4
- ID
- ZDB-GENE-030131-251
- Name
- complement factor H like 4
- Symbol
- cfhl4 Nomenclature History
- Previous Names
-
- cfhl2 (1)
- cfhr2
- im:7037131
- si:ch211-207o17.1
- wu:fb18c08
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Is expressed in several structures, including digestive system; eye; fin; gill; and heart. Orthologous to several human genes including F13B (coagulation factor XIII B chain).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Sun et al., 2010
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Complement System Regulators and Virion Entry Mediators | Sushi/SCR/CCP domain | Sushi/SCR/CCP superfamily |
|---|---|---|---|---|---|
| UniProtKB:A0A8M3AMD6 | InterPro | 499 | |||
| UniProtKB:E2FHP8 | InterPro | 471 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-207O17 | ZFIN Curated Data | |
| Encodes | EST | fb18c08 | ||
| Encodes | EST | IMAGE:7037131 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001199366 (1) | 1677 nt | ||
| Genomic | GenBank:BX005398 (1) | 209859 nt | ||
| Polypeptide | UniProtKB:A0A8M3AMD6 (1) | 499 aa |
- Wu, J., Li, H., and Zhang, S. (2012) Regulator of complement activation (RCA) group 2 gene cluster in zebrafish: identification, expression, and evolution. Functional & integrative genomics. 12(2):367-377
- Wang, Y., and Zhang, S. (2011) Identification and expression of liver-specific genes after LPS challenge in amphioxus: the hepatic cecum as liver-like organ and "pre-hepatic" acute phase response. Functional & integrative genomics. 11(1):111-118
- Sun, G., Li, H., Wang, Y., Zhang, B., and Zhang, S. (2010) Zebrafish complement factor H and its related genes: identification, evolution, and expression. Functional & integrative genomics. 10(4):577-587
- Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314
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