Gene
sin3ab
- ID
- ZDB-GENE-030131-2066
- Name
- SIN3 transcription regulator family member Ab
- Symbol
- sin3ab Nomenclature History
- Previous Names
-
- fb95g11
- wu:fb95g11
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable transcription corepressor activity. Acts upstream of or within heart development. Predicted to be located in nucleus. Predicted to be part of Sin3-type complex. Predicted to be active in chromatin. Human ortholog(s) of this gene implicated in chromosome 15q24 deletion syndrome. Orthologous to human SIN3A (SIN3 transcription regulator family member A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from DeMoya et al., 2023
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| chromosome 15q24 deletion syndrome | Alliance | Witteveen-Kolk syndrome | 613406 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Histone deacetylase interacting domain | Paired amphipathic helix | Paired amphipathic helix superfamily | Sin3, C-terminal | Transcriptional regulatory protein Sin3-like |
|---|---|---|---|---|---|---|
|
UniProtKB:E7F0R9
|
1262 | |||||
|
UniProtKB:A0A8M3B4C3
|
1269 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
sin3ab-201
(1)
|
Ensembl | 5,330 nt | ||
| mRNA |
sin3ab-202
(1)
|
Ensembl | 1,598 nt | ||
| mRNA |
sin3ab-204
(1)
|
Ensembl | 6,698 nt | ||
| ncRNA |
sin3ab-002
(1)
|
Ensembl | 687 nt |
Interactions and Pathways
No data available
Plasmids
No data available