Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-1826
Gene Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Gene Symbol: ace
Previous Names: fb81h03, si:ch211-124e16.1, wu:fb81h03 (1)
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 11 figures (14 images) from Rauch et al., 2003 [fb81h03]
  12 figures (18 images) from Rauch et al., 2003 [fb64c02]
Wild-type Stages, Structures: Segmentation:5-9 somites (11.66h-14.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  adaxial cell, digestive system, endocrine system, eye (all 8) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa12049, sa17717
Knockdown reagents: MO1-ace (1)
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Renal tubular dysgenesis 267430
[Angiotensin I-converting enzyme, benign serum increase]
{Alzheimer disease, susceptibility to} 104300
{Microvascular complications of diabetes 3} 612624
{Myocardial infarction, susceptibility to}
{SARS, progression of}
{Stroke, hemorrhagic} 614519
GENE ONTOLOGY
Ontology GO Term
Biological Process proteolysis (more)
Cellular Component membrane (more)
Molecular Function metallopeptidase activity (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001548 (1)
  • Pfam:PF01401 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ace-001 (1) 4260
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM ace No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    ace Contained in: [BAC] CH211-124E16 (1) (order this), CH211-271E19 (1) (order this)
    ace Encodes: [EST] fb64c02 (1), fb81h03
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_689244 (1) 4349 bp
    Genomic GenBank:CU459092 (1) 147841 bp
    Select Tool
    Polypeptide UniProtKB:E7FFA5 (1) 1324 aa
    Sequence Clusters UniGene:4864 (1)
    Sequence Information (all 14)
    OTHER ace GENE PAGES
  • Gene:565980 (1)
  • VEGA:OTTDARG00000035735 (1)
  • Ensembl(Zv9):ENSDARG00000079166 (1)
  • MAPPING INFORMATION
    Chr: 12 Details
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA
    Zebrafish ace 12  
    Human ACE 17 (17q23.3)
  • OMIM:106180
  • Gene:1636
  • Mouse Ace 11 ( 68.84 cM)
  • MGI:87874
  • Gene:11421
  • CITATIONS (13)