Gene
atg7
- ID
- ZDB-GENE-030131-1633
- Name
- ATG7 autophagy related 7 homolog (S. cerevisiae)
- Symbol
- atg7 Nomenclature History
- Previous Names
-
- fb76g05
- im:7158252
- wu:fb76g05
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have ubiquitin-like modifier activating enzyme activity. Involved in autophagosome assembly; heart development; and mitophagy. Predicted to localize to cytoplasm. Is expressed in brain; liver; and muscle. Orthologous to human ATG7 (autophagy related 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 11 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7158252 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 14 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
autosomal recessive spinocerebellar ataxia 31 | Alliance | Spinocerebellar ataxia, autosomal recessive 31 | 619422 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000594 | THIF-type NAD/FAD binding fold |
Domain | IPR032197 | Ubiquitin-like modifier-activating enzyme Atg7, N-terminal |
Family | IPR006285 | Ubiquitin-like modifier-activating enzyme Atg7 |
Family | IPR045886 | ThiF/MoeB/HesA family |
Homologous_superfamily | IPR035985 | Ubiquitin-activating enzyme |
Homologous_superfamily | IPR042522 | Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 1 |
Homologous_superfamily | IPR042523 | Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 2 |
Domain Details Per Protein
Protein | Length | ThiF/MoeB/HesA family | THIF-type NAD/FAD binding fold | Ubiquitin-activating enzyme | Ubiquitin-like modifier-activating enzyme Atg7 | Ubiquitin-like modifier-activating enzyme Atg7, N-terminal | Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 1 | Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 2 |
---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M9QHT7
|
704 |
Interactions and Pathways
No data available
Plasmids
No data available