Gene

setd6

ID
ZDB-GENE-030131-1067
Name
SET domain containing 6, protein lysine methyltransferase
Symbol
setd6 Nomenclature History
Previous Names
  • wu:fb58f11
  • zgc:55627 (1)
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have NF-kappaB binding activity and protein-lysine N-methyltransferase activity. Predicted to be involved in negative regulation of NF-kappaB transcription factor activity; peptidyl-lysine monomethylation; and regulation of inflammatory response. Predicted to localize to nucleus. Is expressed in several structures, including alar plate midbrain region; anterior neural keel; immature eye; midbrain; and pectoral fin musculature. Orthologous to human SETD6 (SET domain containing 6, protein lysine methyltransferase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With setd6 Human Ortholog
No data available
Associated With setd6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001214 SET domain
Domain IPR015353 Rubisco LSMT, substrate-binding domain
Domain IPR044430 SETD6, SET domain
Family IPR011383 N-lysine methyltransferase SETD6
Homologous_superfamily IPR036464 Rubisco LSMT, substrate-binding domain superfamily
Homologous_superfamily IPR046341 SET domain superfamily
Domain Details Per Protein
Protein Length N-lysine methyltransferase SETD6 Rubisco LSMT, substrate-binding domain Rubisco LSMT, substrate-binding domain superfamily SETD6, SET domain SET domain SET domain superfamily
UniProtKB:Q803K4 460
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations