ZFIN ID: ZDB-GENE-010906-1
Gene Name: acetylcholinesterase
Gene Symbol: ache

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Previous Names: zgc:92550, ziehharmonika (1), zim (1)

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(Including Attributions)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 15 figures from 10 publications
Directly Submitted Expression Data: 6 figures (6 images) from Thisse et al., 2005 [eu3]
Wild-type Stages, Structures: Blastula:Sphere (4.0h-4.33h) to Adult (90d-730d, breeding adult)
  brain, hindbrain, interpeduncular nucleus tegmentum, midbrain (all 11) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa31572 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40891 Point Mutation Unknown Premature Stop ENU
    sb55 Point Mutation Unknown Missense ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tf222a Point Mutation Unknown Missense
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tm205 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tm206 Unknown Unknown Unknown ENU
    Targeting reagents: MO1-ache (1)
    PHENOTYPE
    Data: 16 figures from 6 publications
    Observed in: acetylcholinesterase activity, apoptotic process, associative learning, axon guidance (all 27) expand
    DISEASE ASSOCIATED WITH ache HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    [Blood group, Yt system] 112100
    Ontology GO Term
    Biological Process acetylcholine catabolic process (more)
    Cellular Component cell junction (more)
    Molecular Function acetylcholinesterase activity (more)
    GO Terms (all 21)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000997 (1)
  • InterPro:IPR002018 (1)
  • InterPro:IPR014788 (1)
  • InterPro:IPR019819 (1)
  • InterPro:IPR019826 (1)
  • InterPro:IPR029058 (1)
  • PROSITE:PS00122 (1)
  • PROSITE:PS00941 (1)
  • Pfam:PF00135 (1)
  • Pfam:PF08674 (1)
  • EC:3.1.1.- (1)
  • EC:3.1.1.7 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ache-001 (1) 4795
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ache
    Tg(Cca.Actb:YFP,5xUAS:ache)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    acheContained in: [BAC] CH211-153N19 (1) (order this), CH211-196F2 (1) (order this)
    acheEncodes: [EST] eu3 (1)
    [cDNA] MGC:92550 (1) (order this), MGC:195318 (1) (order this), MGC:195325 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131846 (1) 4825bp
    Genomic GenBank:BX470232 (1) 194721bp
    Select Tool
    Polypeptide UniProtKB:B3DKL4 (1) 634aa
    Sequence Clusters UniGene:133438 (1)
    Sequence Information (all 24)
    OTHER ache GENE PAGES
  • Gene:114549 (1)
  • VEGA:OTTDARG00000020126 (1)
  • Ensembl(GRCz10):ENSDARG00000031796 (1)
  • ORTHOLOGY for ache (Chr: 7)
    CITATIONS (65)