Gene
angpt1
- ID
- ZDB-GENE-010817-1
- Name
- angiopoietin 1
- Symbol
- angpt1 Nomenclature History
- Previous Names
-
- ang1 (1)
- wu:fc76g06
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to have receptor tyrosine kinase binding activity. Involved in blood vessel development and brain development. Human ortholog(s) of this gene implicated in brain ischemia; diabetic retinopathy; and hypertension. Is expressed in several structures, including brain; heart tube; hypochord; medial longitudinal fasciculus; and ventral mesenchyme. Orthologous to human ANGPT1 (angiopoietin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 14 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Angioedema, hereditary, 5 | 619361 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020837 | Fibrinogen, conserved site |
| Domain | IPR002181 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain |
| Homologous_superfamily | IPR014716 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 |
| Homologous_superfamily | IPR036056 | Fibrinogen-like, C-terminal |
Domain Details Per Protein
| Protein | Length | Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain | Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 | Fibrinogen, conserved site | Fibrinogen-like, C-terminal |
|---|---|---|---|---|---|
|
UniProtKB:Q90Z19
|
513 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
angpt1-201
(1)
|
Havana | 2164 nt |
Interactions and Pathways
No data available
Plasmids
No data available