Gene

six2a

ID
ZDB-GENE-010412-1
Name
SIX homeobox 2a
Symbol
six2a Nomenclature History
Previous Names
  • six2.1
  • wu:fj04e08
  • zgc:91945
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and transcription regulatory region sequence-specific DNA binding activity. Involved in pronephros development. Predicted to localize to nucleus and transcription factor complex. Is expressed in head mesenchyme; immature eye; intermediate mesoderm; and nervous system. Orthologous to human SIX2 (SIX homeobox 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Weber et al., 2008
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With six2a Human Ortholog
No data available
Associated With six2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeodomain
Domain IPR008422 KN homeodomain
Domain IPR031701 Homeobox protein SIX1, N-terminal SD domain
Homologous_superfamily IPR009057 Homedomain-like superfamily
Domain Details Per Protein
Protein Length Homedomain-like superfamily Homeobox, conserved site Homeobox protein SIX1, N-terminal SD domain Homeodomain KN homeodomain
UniProtKB:Q98TH1 288
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA six2a-201 (1) Ensembl 1,609 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations