Gene
badb
- ID
- ZDB-GENE-000616-1
- Name
- BCL2 associated agonist of cell death b
- Symbol
- badb Nomenclature History
- Previous Names
-
- bad
- fa01b12
- proapoptotic BH3-only protein
- wu:fa01b12
- wu:fa96d04
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Involved in cellular response to ionizing radiation and positive regulation of apoptotic process. Localizes to mitochondrion. Human ortholog(s) of this gene implicated in endometrial cancer; lung non-small cell carcinoma; and pancreatic cancer. Is expressed in several structures, including brain; heart; hindbrain neural plate; midbrain hindbrain boundary neural keel; and pleuroperitoneal region. Orthologous to human BAD (BCL2 associated agonist of cell death).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 23 figures from 13 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:114031 (7 images)
- eu145 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- 6 figures from Hung et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR018868 | Bcl2-associated agonist of cell death |
Domain Details Per Protein
| Protein | Length | Bcl2-associated agonist of cell death |
|---|---|---|
|
UniProtKB:Q9I9N2
|
146 | |
|
UniProtKB:Q4V925
|
147 |
Interactions and Pathways
No data available
Plasmids
No data available