Gene
pycard
- ID
- ZDB-GENE-000511-2
- Name
- PYD and CARD domain containing
- Symbol
- pycard Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Exhibits Pyrin domain binding activity. Involved in defense response to bacterium; innate immune response; and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process. Predicted to localize to cytoplasm. Is expressed in several structures, including digestive system; immune system; integument; periderm; and unfertilized egg. Orthologous to human PYCARD (PYD and CARD domain containing).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 21 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:109874 (8 images)
- eu1007 (8 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | CARD8/ASC/NALP1, CARD domain | CARD domain | DAPIN domain | Death-like domain superfamily | NLRP Inflammasome |
|---|---|---|---|---|---|---|
|
UniProtKB:Q9I9N6
|
203 | |||||
|
UniProtKB:Q4VBV3
|
203 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pycard-201
(1)
|
Ensembl | 916 nt |
Interactions and Pathways
No data available
Plasmids