Gene
smarcad1a
- ID
- ZDB-GENE-050522-499
- Name
- SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 a
- Symbol
- smarcad1a Nomenclature History
- Previous Names
-
- smarcad1
- wu:fi25c01
- zgc:113183
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to be involved in ATP-dependent chromatin remodeling and DNA double-strand break processing. Predicted to localize to site of double-strand break. Human ortholog(s) of this gene implicated in adermatoglyphia. Orthologous to human SMARCAD1 (SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Han et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
adermatoglyphia | Alliance | Adermatoglyphia | 136000 |
BASAN syndrome | Alliance | Basan syndrome | 129200 |
Huriez syndrome | 181600 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000330 | SNF2, N-terminal |
Domain | IPR001650 | Helicase, C-terminal domain-like |
Domain | IPR003892 | Ubiquitin system component CUE |
Domain | IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
Homologous_superfamily | IPR009060 | UBA-like superfamily |
Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Homologous_superfamily | IPR038718 | SNF2-like, N-terminal domain superfamily |
Domain Details Per Protein
Protein | Length | Helicase, C-terminal domain-like | Helicase superfamily 1/2, ATP-binding domain | P-loop containing nucleoside triphosphate hydrolase | SNF2-like, N-terminal domain superfamily | SNF2, N-terminal | UBA-like superfamily | Ubiquitin system component CUE |
---|---|---|---|---|---|---|---|---|
UniProtKB:B0R061
|
972 | |||||||
UniProtKB:A0A8M1N6H2
|
972 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
smarcad1a-201
(1)
|
Havana | 3644 nt | |
mRNA |
smarcad1a-202
(1)
|
Havana | 600 nt | |
mRNA |
smarcad1a-203
(1)
|
Havana | 2151 nt | |
ncRNA |
smarcad1a-004
(1)
|
Havana | 491 nt | |
ncRNA |
smarcad1a-005
(1)
|
Havana | 479 nt |
Interactions and Pathways
No data available
Plasmids
No data available