ZFIN ID: ZDB-GENE-020123-2
Gene Name: sphingosine-1-phosphate receptor 2
Gene Symbol: s1pr2
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function G protein-coupled receptor activity IEA InterPro:IPR000276 ZFIN Electronic Annotation
G protein-coupled receptor activity IEA UniProtKB-KW:KW-0297 ZFIN Electronic Annotation
sphingosine-1-phosphate receptor activity IEA InterPro:IPR004061 ZFIN Electronic Annotation
sphingosine-1-phosphate receptor activity IEA InterPro:IPR004063 ZFIN Electronic Annotation
Cellular Component integral component of membrane IEA InterPro:IPR000276 ZFIN Electronic Annotation
integral component of membrane IEA InterPro:IPR004061 ZFIN Electronic Annotation
integral component of membrane IEA InterPro:IPR004063 ZFIN Electronic Annotation
integral component of membrane IEA InterPro:IPR017452 ZFIN Electronic Annotation
integral component of membrane IEA UniProtKB-KW:KW-0812 ZFIN Electronic Annotation
membrane IEA UniProtKB-KW:KW-0472 ZFIN Electronic Annotation
plasma membrane IEA UniProtKB-KW:KW-1003 ZFIN Electronic Annotation
plasma membrane IEA UniProtKB-SubCell:SL-0039 UniProt-GOA
Biological Process anterior lateral line neuromast development IMP MO1-s1pr2 Hu et al., 2013
anterior lateral line neuromast hair cell development IMP MO1-s1pr2 Hu et al., 2013
cardioblast migration to the midline involved in heart rudiment formation IGI MO1-s1pr2, fn1akt259/kt259 Hisano et al., 2013
cardioblast migration to the midline involved in heart rudiment formation IGI s1pr2ko322/ko322 , MO1-fn1a Hisano et al., 2013
cardioblast migration to the midline involved in heart rudiment formation IMP s1pr2ko322/ko322 Hisano et al., 2013
cell migration involved in gastrulation IGI MO1-s1pr1, MO1-s1pr2 Kai et al., 2008
cell migration involved in gastrulation IMP MO1-s1pr2 Kai et al., 2008
cell migration involved in heart development IMP MO1-s1pr2 Ye et al., 2013
cell migration involved in heart development IMP s1pr2m93/m93 Ye et al., 2013
cell migration to the midline involved in heart development IMP s1pr2m93/m93 Mendelson et al., 2015
convergent extension IMP s1pr2m93/m93 Ye et al., 2013
convergent extension involved in gastrulation IDA Osborne et al., 2008
embryonic heart tube development IMP MO1-s1pr2 Hisano et al., 2013
embryonic heart tube development IMP TALEN1-s1pr2 Hisano et al., 2013
embryonic heart tube morphogenesis IGI MO1-s1pr2, enpp2 Nakanaga et al., 2014
embryonic heart tube morphogenesis IMP MO1-s1pr2 Nakanaga et al., 2014
embryonic viscerocranium morphogenesis IGI MO1-fn1a, s1pr2ko322/ko322 Hisano et al., 2013
embryonic viscerocranium morphogenesis IGI MO1-s1pr2, fn1akt259/kt259 Hisano et al., 2013
endoderm development IMP MO1-s1pr2 Ye et al., 2013
endoderm development IMP s1pr2m93/m93 Ye et al., 2013
G protein-coupled receptor signaling pathway IEA InterPro:IPR000276 ZFIN Electronic Annotation
G protein-coupled receptor signaling pathway IEA InterPro:IPR004061 ZFIN Electronic Annotation
G protein-coupled receptor signaling pathway IEA InterPro:IPR004063 ZFIN Electronic Annotation
G protein-coupled receptor signaling pathway IEA UniProtKB-KW:KW-0297 ZFIN Electronic Annotation
heart development IMP s1pr2te273/te273 Holtzman et al., 2007
heart morphogenesis IGI MO4-fn1a, s1pr2te273/te273; twu34Tg/twu34Tg Matsui et al., 2007
heart morphogenesis IMP s1pr2m93/m93 Chen et al., 1996
heart morphogenesis IMP s1pr2te273/te273; twu34Tg/twu34Tg Matsui et al., 2007
heart morphogenesis IMP s1pr2te273/te273 Chen et al., 1996
heart rudiment formation IGI s1pr2m93/m93 , MO1-grk3 Burczyk et al., 2015
heart rudiment formation IMP s1pr2m93/m93 Burczyk et al., 2015
mesodermal cell migration IGI MO1-s1pr2, wnt11tx226/tx226 Kai et al., 2008
negative regulation of cell migration IGI MO1-s1pr2, MO1-s1pr1 Kai et al., 2008
negative regulation of cell migration IMP MO1-s1pr2 Kai et al., 2008
otolith development IMP MO1-s1pr2 Hu et al., 2013
posterior lateral line neuromast hair cell development IMP MO1-s1pr2 Hu et al., 2013
regulation of cartilage development IMP s1pr2m93/m93 Balczerski et al., 2012
semicircular canal development IMP MO1-s1pr2 Hu et al., 2013
signal transduction IEA UniProtKB-KW:KW-0807 ZFIN Electronic Annotation
sphingosine-1-phosphate receptor signaling pathway IMP s1pr2m93/m93 Balczerski et al., 2012
vasculature development IGI MO1-s1pr2, MO2-s1pr1 Mendelson et al., 2013