ZFIN

ZFIN ID: ZDB-TGCONSTRCT-110127-2

CITATIONS (16 total)

Transgenic Construct Name:	Tg(mitfa:Hsa.HRAS_G12V,mitfa:GFP)
Transgenic Construct Symbol:	Tg(mitfa:Hsa.HRAS_G12V,mitfa:GFP)

Espigares, F., Alvarado, M.V., Abad-Tortosa, D., Varela, S.A.M., Sobral, D., Faísca, P., Paixão, T., Oliveira, R.F. (2025) Optimistic and pessimistic cognitive judgement bias modulates the stress response and cancer progression in zebrafish. Translational psychiatry. 15:111

Lopes-Bastos, B., Nabais, J., Ferreira, T., Allavena, G., El Maï, M., Bird, M., Targen, S., Tattini, L., Kang, D., Yue, J.X., Liti, G., Carvalho, T.G., Godinho Ferreira, M. (2024) The absence of telomerase leads to immune response and tumor regression in zebrafish melanoma. Cell Reports. 43:115035

Katkat, E., Demirci, Y., Heger, G., Karagulle, D., Papatheodorou, I., Brazma, A., Ozhan, G. (2023) Canonical Wnt and TGF-β/BMP signaling enhance melanocyte regeneration but suppress invasiveness, migration, and proliferation of melanoma cells. Frontiers in cell and developmental biology. 11:1297910

Wilcock, D.J., Badrock, A.P., Wong, C.W., Owen, R., Guerin, M., Southam, A.D., Johnston, H., Telfer, B.A., Fullwood, P., Watson, J., Ferguson, H., Ferguson, J., Lloyd, G.R., Jankevics, A., Dunn, W.B., Wellbrock, C., Lorigan, P., Ceol, C., Francavilla, C., Smith, M.P., Hurlstone, A.F.L. (2022) Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached. Cell Reports. 39:110995

Lex, K., Maia Gil, M., Lopes-Bastos, B., Figueira, M., Marzullo, M., Giannetti, K., Carvalho, T., Ferreira, M.G. (2020) Telomere shortening produces an inflammatory environment that increases tumor incidence in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 117(26):15066-15074

Henderson, F., Johnston, H.R., Badrock, A.P., Jones, E.A., Forster, D., Nagaraju, R.T., Evangelou, C., Kamarashev, J., Green, M., Fairclough, M., Barinaga-Rementeria Ramirez, I., He, S., Snaar-Jagalska, B.E., Hollywood, K., Dunn, W.B., Spaink, H.P., Smith, M.P., Lorigan, P., Claude, E., Williams, K.J., McMahon, A.W., Hurlstone, A. (2019) Enhanced fatty acid scavenging and glycerophospholipid metabolism accompanies melanocyte neoplasia progression in zebrafish. Cancer research. 79(9):2136-2151

Dee, C.T., Nagaraju, R.T., Athanasiadis, E.I., Gray, C., Fernandez Del Ama, L., Johnston, S.A., Secombes, C.J., Cvejic, A., Hurlstone, A.F. (2016) CD4-Transgenic Zebrafish Reveal Tissue-Resident Th2- and Regulatory T Cell-like Populations and Diverse Mononuclear Phagocytes. Journal of immunology (Baltimore, Md. : 1950). 197(9):3520-3530

Fernandez Del Ama, L., Jones, M., Walker, P., Chapman, A., Braun, J.A., Mohr, J., Hurlstone, A.F. (2016) Reprofiling using a zebrafish melanoma model reveals drugs cooperating with targeted therapeutics. Oncotarget. 7(26):40348-40361

Mouti, M.A., Dee, C., Coupland, S.E., Hurlstone, A.F. (2016) Minimal contribution of ERK1/2-MAPK signalling towards the maintenance of oncogenic GNAQQ209P-driven uveal melanomas in zebrafish. Oncotarget. 7(26):39654-39670

Hamilton, N., Diaz-de-Cerio, N., Whitmore, D. (2015) Impaired light detection of the circadian clock in a zebrafish melanoma model. Cell cycle (Georgetown, Tex.). 14(8):1232-41

Herrero, A., Pinto, A., Colón-Bolea, P., Casar, B., Jones, M., Agudo-Ibáñez, L., Vidal, R., Tenbaum, S.P., Nuciforo, P., Valdizán, E.M., Horvath, Z., Orfi, L., Pineda-Lucena, A., Bony, E., Keri, G., Rivas, G., Pazos, A., Gozalbes, R., Palmer, H.G., Hurlstone, A., Crespo, P. (2015) Small Molecule Inhibition of ERK Dimerization Prevents Tumorigenesis by RAS-ERK Pathway Oncogenes. Cancer Cell. 28:170-82

Dalton, L.E., Kamarashev, J., Ramirez, I.R., White, G., Malliri, A., and Hurlstone, A. (2013) Constitutive Rac Activation is not Sufficient to Initiate Melanocyte Neoplasia but Accelerates Malignant Progression. The Journal of investigative dermatology. 133(6):1572-81

Kabli, S., He, S., Spaink, H.P., Hurlstone, A., Jagalska, E.S., De Groot, H.J., and Alia, A. (2010) In vivo magnetic resonance imaging to detect malignant melanoma in adult zebrafish. Zebrafish. 7(2):143-148

Michailidou, C., Jones, M., Walker, P., Kamarashev, J., Kelly, A., and Hurlstone, A.F. (2009) Dissecting the roles of Raf- and PI3K-signalling pathways in melanoma formation and progression in a zebrafish model. Disease models & mechanisms. 2(7-8):399-411

Additional Citations (2):

ZFIN Staff (2015) Data Model Change: Sequence Targeting Reagents Removed from Environment. ZFIN Historical Data.

ZFIN Staff (2002) Scientific Curation. Manually curated data.