FIGURE SUMMARY
Title

Discordant Effects of Putative Lysine Acetyltransferase Inhibitors in Biochemical and Living Systems

Authors
Henry, R.A., Kuo, Y.M., Siegel, Z.S., Yen, T.J., Rhodes, J., Taylor, E.A., Andrews, A.J.
Source
Full text @ Cells

Drug treatment of zebrafish embryos. Zebrafish embryos were collected and treated for 24 h with drug. The survival rates at 6 h for (A) garcinol and (B) CTB, 24 h for (C) EGCG, (D) CTPB, and (E) C646 were measured. (F) Representative pictures of the phenotypes found at these time points. Histone acetylation levels of embryos treated with C646 were measured at 24 h. Shown are the fraction of acetylation at (G) H3K9, (H) H3K14, (I) H3K18, and (J) H3K23. This experiment was performed in triplicate, and data are represented as mean ± SEM. (*) p < 0.05, (**) p < 0.005 when compared to the untreated control, unless the comparison is otherwise indicated.

Acknowledgments
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