FIGURE SUMMARY
- Title
-
Genetic Pathways of Neuroregeneration in a Novel Mild Traumatic Brain Injury Model in Adult Zebrafish
- Authors
- Maheras, A.L., Dix, B., Carmo, O.M.S., Young, A.E., Gill, V.N., Sun, J.L., Booker, A.R., Thomason, H.A., Ibrahim, A.E., Stanislaw, L., Dallego, J.C., Ngo, C.N., Chen, A., Fortini, B.K., Spence, R.D.
- Source
- Full text @ eNeuro
The mTBI weight-drop model for adult zebrafish. This novel model allows administration of a nonpenetrating, diffuse injury to the brain of an adult zebrafish. The fish are anesthetized in 0.02% tricaine-S (MS-222), placed on the foam cradle, and given a strike from a 0.33-g ball bearing, delivering a force of 0.0032 N and an impact energy of 35 mJ. The bottom of the guide tube is fixed ∼1 cm above the zebrafish cranium, ensuring impact in a targeted location between the eyes of the fish. |
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Full text @ eNeuro