| ZFIN ID: ZDB-EXP-240125-7 |
Experiment Conditions Description: chemical treatment by environment: etacrynic acid
| chemical treatment by environment: etacrynic acid |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | etacrynic acid |
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| Synonyms: | (2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy)acetic acid, [2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid, acide etacrynique, acido etacrinico, acidum etacrynicum, Crinuryl, Edecril, Edecrina, Endecril, Etacrinic acid, etacrynic acid, Ethacrynate, ethacrynic acid, Hidromedin, Hydromedin, Methylenebutyrylphenoxyacetic acid, Mingit, Otacril, Reomax, Taladren, Uregit |
| Definition: | An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor. |
| Ontology: | ChEBI [CHEBI:4876] ( EBI ) |
| Publication: | Coffin et al., 2010 |
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