| ZFIN ID: ZDB-EXP-231114-8 |
Experiment Conditions Description: chemical treatment by environment: cisplatin
| chemical treatment by environment: cisplatin |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | cisplatin |
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| Synonyms: | (SP-4-2)-diamminedichloridoplatinum, (SP-4-2)-diamminedichloroplatinum, [PtCl2(NH3)2], Briplatin, CDDP, cis-[PtCl2(NH3)2], cis-DDP, cis-diamminedichloridoplatinum(II), cis-diamminedichloroplatinum, cis-diamminedichloroplatinum(II), cis-diammineplatinum(II) dichloride, cis-dichlorodiammineplatinum(II), cis-platin, Cismaplat, cisplatin, cisplatine, cisplatino, cisplatinum, Lederplatin, Neoplatin, Peyrone's chloride, Peyrone's salt, Platamine, Platinex, Platinol, Randa |
| Definition: | A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups). |
| Ontology: | ChEBI [CHEBI:27899] ( EBI ) |
| Publication: | Naylor et al., 2022 |
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