ZFIN ID: ZDB-EXP-230214-4
Experiment Conditions Description: transection: spinal cord, chemical treatment by environment: doxycycline
transection: spinal cord
Name: transection
Synonyms:
Definition: Cutting transversly of an organ or tissue. Type of cutting often used to divide the spinal cord to investigate neural regeneration in zebrafish.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000181]
Name: spinal cord
Synonyms: medulla spinalis, spinal cord structure
Definition:
Ontology: Anatomy Ontology [ZFA:0000075]
chemical treatment by environment: doxycycline
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: doxycycline
Synonyms: (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, 5-hydroxy-alpha-6-deoxytetracycline, 6alpha-deoxy-5-oxytetracycline, doxiciclina, Doxycyclin, Doxycycline, doxycycline (anhydrous), doxycyclinum, Jenacyclin, Supracyclin, Vibramycin
Definition: Tetracycline in which the 5beta-hydrogen is replaced by a hydroxy group, while the 6alpha-hydroxy group is replaced by hydrogen. A semi-synthetic tetracycline antibiotic, it is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with chronic obstructive pulmonary disease (COPD), and adult periodontitis.
Ontology: ChEBI [CHEBI:50845]  ( EBI )
Publication: Tsata et al., 2020