ZFIN ID: ZDB-EXP-220629-4
Experiment Conditions Description: chemical treatment by injection: gonadotropin releasing hormone agonist, chemical treatment by injection: domperidone, chemical treatment by injection: prostaglandin receptor antagonist
chemical treatment by injection: gonadotropin releasing hormone agonist
Name: chemical treatment by injection
Synonyms:
Definition: Chemical treatment in which the chemical is injected into the zebrafish.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000237]
Name: gonadotropin releasing hormone agonist
Synonyms: GnRH agonist, GnRH agonists, GnRH-A, gonadotrophin releasing hormone agonist, gonadotrophin releasing hormone agonists, gonadotropin releasing hormone agonists
Definition: Any drug which binds to gonadotropin-releasing hormone receptors and triggers a response.
Ontology: ChEBI [CHEBI:63533]  ( EBI )
chemical treatment by injection: domperidone
Name: chemical treatment by injection
Synonyms:
Definition: Chemical treatment in which the chemical is injected into the zebrafish.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000237]
Name: domperidone
Synonyms: 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one, 5-chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinone, 5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one, 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one, 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one, domperidona, domperidone, domperidonum
Definition: 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Ontology: ChEBI [CHEBI:31515]  ( EBI )
chemical treatment by injection: prostaglandin receptor antagonist
Name: chemical treatment by injection
Synonyms:
Definition: Chemical treatment in which the chemical is injected into the zebrafish.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000237]
Name: prostaglandin receptor antagonist
Synonyms: prostaglandin receptor antagonists, prostanoid receptor antagonist, prostanoid receptor antagonists
Definition: An antagonist that binds to and blocks the activity of prostaglandin receptors.
Ontology: ChEBI [CHEBI:138887]  ( EBI )
Publication: Baker et al., 2019