ZFIN ID: ZDB-EXP-220407-2
Experiment Conditions Description: chemical treatment: imetit dihydrobromide
chemical treatment: imetit dihydrobromide
Name: chemical treatment
Synonyms:
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: imetit dihydrobromide
Synonyms: 2-(1H-imidazol-4-yl)ethyl carbamimidothioate dihydrobromide, imetit hydrobromide, S-{2-[1H-imidazol-4-yl]ethyl}isothiourea dihydrobromide
Definition: A hydrobromide salt obtained by reaction of imetit with two equivalents of hydrobromic acid. An extremely potent, high affinity agonist at H3 and H4 receptors (Ki values are 0.3 and 2.7 nM respectively). Induces shape change in eosinophils with an EC50 of 25 nM. Centrally active following systemic administration.
Ontology: ChEBI [CHEBI:64151]  ( EBI )
Publication: Norton et al., 2011