ZFIN ID: ZDB-EXP-190708-8
Experiment Conditions Description: chemical treatment by environment: 17alpha-estradiol, chemical treatment by environment: fulvestrant
chemical treatment by environment: 17alpha-estradiol
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: 17alpha-estradiol
Synonyms: (17alpha)-estra-1,3,5(10)-triene-3,17-diol, 1,3,5-estratriene-3,17alpha-diol, 13beta-methyl-1,3,5(10)-gonatriene-3,17alpha-diol, 17-epiestradiol, 17alpha-Estradiol, 17alpha-oestradiol, 3,17alpha-dihydroxyestra-1,3,5(10)-triene, 3,17alpha-dihydroxyoestra-1,3,5(10)-triene, alfatradiol, alfatradiolum, alpha-estradiol, epiestradiol, epiestrol, estra-1,3,5(10)-triene-3,17alpha-diol, estra-1,3,5(10)trien-3,17alpha-diol, Estradiol-17alpha, oestra-1,3,5(10)-triene-3,17alpha-diol
Definition: An estradiol that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 17 (the 17alpha stereoisomer).
Ontology: ChEBI [CHEBI:17160]  ( EBI )
chemical treatment by environment: fulvestrant
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: fulvestrant
Synonyms: (7alpha,17beta)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17-diol, 7alpha-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17beta-diol, Faslodex, fulvestrant, fulvestrantum, ICI 182780, ICI-182780
Definition: A 3-hydroxy steroid that is 17beta-estradiol in which the 7alpha hydrogen has been replaced by a nonyl group in which one of the hydrogens of the terminal methyl has been replaced by a (4,4,5,5,5-pentafluoropentyl)sulfinyl group. An estrogen receptor antagonist, it is used in the treatment of breast cancer.
Ontology: ChEBI [CHEBI:31638]  ( EBI )
Publication: Carroll et al., 2014