| ZFIN ID: ZDB-EXP-190502-3 |
Experiment Conditions Description: chemical treatment: substance P, chemical treatment: serotonergic antagonist
| chemical treatment: substance P |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | substance P |
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| Synonyms: | Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2, H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2, L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-L-methioninamide, RPKPQQFFGLM-amide, RPKPQQFFGLM-NH2 |
| Definition: | A neuropeptide consisting of 11-amino acids. It preferentially activates neurokinin-1 receptors, exterting excitatory effects on central and peripheral neurons and involved in pain transmission. |
| Ontology: | ChEBI [CHEBI:80308] ( EBI ) |
| chemical treatment: serotonergic antagonist |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | serotonergic antagonist |
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| Synonyms: | 5-HT antagonists, 5-hydroxytryptamine antagonists, antiserotonergic agents, serotonin antagonists, serotonin blockaders |
| Definition: | Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists. |
| Ontology: | ChEBI [CHEBI:48279] ( EBI ) |
| Publication: | Wu et al., 2018 |
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