| ZFIN ID: ZDB-EXP-180531-13 |
Experiment Conditions Description: chemical treatment by environment: 1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea
| chemical treatment by environment: 1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | 1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea |
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| Synonyms: | 1-(1-methyl-1H-indol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea, 3-(3-methyl-1,2-thiazol-5-yl)-1-(1-methylindol-5-yl)urea, N-(1-methyl-1H-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea, N-(1-methyl-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea, SB 204741, SB-204741, SB204741 |
| Definition: | A member of ther class of ureas that is urea in which a hydrogen attached to one of the nitrogens has been replaced by an N-methylindol-5-yl group, while a hydrogen attached to the other nitrogen has been replaced by a 3-methyl-1,2-thiazol-5-yl group. It is a potent and selective antagonist for the 5-hydroxytryptamine 2B (5-HT2B) receptor. |
| Ontology: | ChEBI [CHEBI:140936] ( EBI ) |
| Publication: | Sourbron et al., 2017 |
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