| ZFIN ID: ZDB-EXP-180510-3 |
Experiment Conditions Description: bacterial treatment by injection: Mycobacteroides abscessus, chemical treatment by environment: bedaquiline
| bacterial treatment by injection: Mycobacteroides abscessus |
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| Name: | bacterial treatment by injection |
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| Synonyms: | |
| Definition: | Bacterial treatment where the bacteria are injected into the fish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000230] |
| Name: | Mycobacteroides abscessus |
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| Synonyms: | "Mycobacterium abcessus" Moore and Frerichs 1953, "Mycobacterium chelonei" (sic) Bergey et al. 1923, Mycobacterium abscessus, Mycobacterium chelonae subsp. abscessus, Mycobacterium chelonei subsp. abscessus |
| Definition: | |
| Ontology: | Taxonomy for ZECO [NCBITaxon:36809] |
| chemical treatment by environment: bedaquiline |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | bedaquiline |
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| Synonyms: | (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(1-naphthyl)-1-phenylbutan-2-ol, 1-(6-Bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-naphthalen-1-yl-1-phenyl-butan-2-ol, bedaquilina, bedaquiline, bedaquilinum, R 207910, R207910, TMC 207, TMC-207, TMC207 |
| Definition: | A quinoline-based antimycobacterial drug used (as its fumarate salt) for the treatment of pulmonary multi-drug resistant tuberculosis by inhibition of ATP synthase, an enzyme essential for the replication of the mycobacteria. |
| Ontology: | ChEBI [CHEBI:72292] ( EBI ) |
| Publication: | Dupont et al., 2017 |
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