| ZFIN ID: ZDB-EXP-101201-2 |
Experiment Conditions Description: physical alteration: anatomical structure, chemical treatment: SU5402
| physical alteration: anatomical structure |
|---|
| Name: | physical alteration |
|---|---|
| Synonyms: | |
| Definition: | Experimental condition in which an anatomical structure, cell, or organ has sustained targeted physical change, usually through the use of an instrument. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000229] |
| Name: | anatomical structure |
|---|---|
| Synonyms: | anatomical structures |
| Definition: | Zebrafish anatomical entity that has inherent 3D shape and is generated by coordinated expression of the organism's own genome. |
| Ontology: | Anatomy Ontology [ZFA:0000037] |
| chemical treatment: SU5402 |
|---|
| Name: | chemical treatment |
|---|---|
| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | SU5402 |
|---|---|
| Synonyms: | 3-[3-(2-carboxyethyl)-4-methylpyrrol-2-methylidenyl]-2-indolinone, 3-{4-methyl-2-[(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl}propanoic acid, 3-{[3-(2-carboxyethyl)-4-methylpyrrol-2-yl]methylene}-2-indolinone, SU 5402, SU-5402 |
| Definition: | An oxindole that is 3-methyleneoxindole in which one of the hydrogens of the methylene group is substituted by a 3-(2-carboxyethyl)-4-methyl-1H-pyrrol-2-yl group. It is an ATP-competitive inhibitor of the tyrosine kinase activity of fibroblast growth factor receptor 1. |
| Ontology: | ChEBI [CHEBI:63449] ( EBI ) |
| Publication: | Bouzaffour et al., 2009 |
|---|