ZFIN ID: ZDB-EXP-070731-6 |
Experiment Conditions Description: chemical treatment: fulvestrant, chemical treatment: testosterone
chemical treatment: fulvestrant |
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Name: | chemical treatment |
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Synonyms: | |
Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
Name: | fulvestrant |
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Synonyms: | (7alpha,17beta)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17-diol, 7alpha-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17beta-diol, Faslodex, fulvestrant, fulvestrantum, ICI 182780, ICI-182780 |
Definition: | A 3-hydroxy steroid that is 17beta-estradiol in which the 7alpha hydrogen has been replaced by a nonyl group in which one of the hydrogens of the terminal methyl has been replaced by a (4,4,5,5,5-pentafluoropentyl)sulfinyl group. An estrogen receptor antagonist, it is used in the treatment of breast cancer. |
Ontology: | ChEBI [CHEBI:31638] ( EBI ) |
chemical treatment: testosterone |
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Name: | chemical treatment |
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Synonyms: | |
Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
Name: | testosterone |
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Synonyms: | 17beta-Hydroxy-4-androsten-3-one, 17beta-hydroxyandrost-4-en-3-one, 4-androsten-17beta-ol-3-one, Androderm, Testosteron, testosterona, testosterone, testosteronum |
Definition: | An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5.. |
Ontology: | ChEBI [CHEBI:17347] ( EBI ) |
Publication: | Lassiter et al., 2007 |
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