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ZFIN ID:
ZDB-ATB-081208-2
CITATIONS
(54 total)
Antibody Name:
Ab3-akt
Allers, M., Bakker, P.A., Hoeksma, J., Spaink, H.P., den Hertog, J. (2023) Loss of Shp1 impairs myeloid cell function and causes lethal inflammation in zebrafish larvae. Disease models & mechanisms. 16(2):
Angulo-Urarte, A., Casado, P., Castillo, S.D., Kobialka, P., Kotini, M.P., Figueiredo, A.M., Castel, P., Rajeeve, V., Milà-Guasch, M., Millan, J., Wiesner, C., Serra, H., Muixi, L., Casanovas, O., Viñals, F., Affolter, M., Gerhardt, H., Huveneers, S., Belting, H.G., Cutillas, P.R., Graupera, M. (2018) Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility. Nature communications. 9:4826
Cao, L., Fang, H., Yan, D., Wu, X.M., Zhang, J., Chang, M.X. (2022) CD44a functions as a regulator of p53 signaling, apoptosis and autophagy in the antibacterial immune response. Communications biology. 5:889
Castranova, D., Davis, A.E., Lo, B.D., Miller, M.F., Paukstelis, P.J., Swift, M.R., Pham, V.N., Torres-Vázquez, J., Bell, K., Shaw, K.M., Kamei, M., Weinstein, B.M. (2016) Aminoacyl-Transfer RNA Synthetase Deficiency Promotes Angiogenesis via the Unfolded Protein Response Pathway. Arteriosclerosis, Thrombosis, and Vascular Biology. 36(4):655-62
Chaturantabut, S., Shwartz, A., Evason, K.J., Cox, A.G., Labella, K., Schepers, A.G., Yang, S., Aravena, M., Houvras, Y., Mancio-Silva, L., Romano, S., Gorelick, D.A., Cohen, D.E., Zon, L.I., Bhatia, S.N., North, T.E., Goessling, W. (2019) Estrogen Activation of G protein-coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes. Gastroenterology. 156(6):1788-1804.e13
Choorapoikayil, S., Kuiper, R.V., de Bruin, A., and den Hertog, J. (2012) Haploinsufficiency of tumor suppressor pten predisposes to hemangiosarcoma in zebrafish. Disease models & mechanisms. 5(2):241-247
Chung, C.K., and Ge, W. (2013) Human chorionic gonadotropin (hCG) induces MAPK3/1 phosphorylation in the zebrafish ovarian follicle cells independent of EGF/EGFR pathway. General and comparative endocrinology. 188:251-7
Chung, C.K., and Ge, W. (2012) Epidermal growth factor differentially regulates activin subunits in the zebrafish ovarian follicle cells via diverse signaling pathways. Molecular and Cellular Endocrinology. 361(1-2):133-142
Daly, C., Shine, L., Heffernan, T., Deeti, S., Reynolds, A.L., O'Connor, J.J., Dillon, E.T., Duffy, D.J., Kolch, W., Cagney, G., Kennedy, B.N. (2017) A Brain-Derived Neurotrophic Factor Mimetic Is Sufficient to Restore Cone Photoreceptor Visual Function in an Inherited Blindness Model. Scientific Reports. 7:11320
de Souza, B.R., Romano-Silva, M.A., and Tropepe, V. (2011) Dopamine d2 receptor activity modulates akt signaling and alters GABAergic neuron development and motor behavior in zebrafish larvae. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31(14):5512-5525
El Maï, M., Marzullo, M., de Castro, I.P., Ferreira, M.G. (2020) Opposing p53 and mTOR/AKT promote an in vivo switch from apoptosis to senescence upon telomere shortening in zebrafish. eLIFE. 9:
Fang, L., Harkewicz, R., Hartvigsen, K., Wiesner, P., Choi, S.H., Almazan, F., Pattison, J., Deer, E., Sayaphupha, T., Dennis, E.A., Witztum, J.L., Tsimikas, S., and Miller, Y.I. (2010) Oxidized cholesteryl esters and phospholipids in zebrafish larvae fed a high cholesterol diet: macrophage binding and activation.. The Journal of biological chemistry. 285(42):32343-32351
Fei, F., Sun, S., Li, Q., Pei, Z., Wang, L., Zhang, R., Luo, F., Yu, M., Wang, X. (2020) Combinatorial normalization of liver-derived cytokine pathways alleviates hepatic tumor-associated cachexia in zebrafish. Cancer research. 81(4):873-884
Fernandez Del Ama, L., Jones, M., Walker, P., Chapman, A., Braun, J.A., Mohr, J., Hurlstone, A.F. (2016) Reprofiling using a zebrafish melanoma model reveals drugs cooperating with targeted therapeutics. Oncotarget. 7(26):40348-40361
Fish, J.E., Flores-Suarez, C.P., Boudreau, E., Herman, A.M., Gutierrez, M.C., Gustafson, D., DiStefano, P.V., Cui, M., Chen, Z., Berman De Ruiz, K., Schexnayder, T.S., Ward, C.S., Radovanovic, I., Wythe, J.D. (2020) Somatic Gain of KRAS Function in the Endothelium is Sufficient to Cause Vascular Malformations that Require MEK but not PI3K Signaling. Circulation research. 127(6):727-743
Han, C.R., Holmsen, E., Carrington, B., Bishop, K., Zhu, Y.J., Starost, M., Meltzer, P., Sood, R., Liu, P., Cheng, S.Y. (2020) Generation of novel genetic models to dissect resistance to thyroid hormone receptor alpha in zebrafish. Thyroid : official journal of the American Thyroid Association. 30(2):314-328
Kamei, H., Yoneyama, Y., Hakuno, F., Sawada, R., Shimizu, T., Duan, C., Takahashi, S.I. (2018) Catch-up growth in zebrafish embryo requires neural crest cells sustained by Irs1-signaling. Endocrinology. 159(4):1547-1560
Kempers, L., Wakayama, Y., van der Bijl, I., Furumaya, C., De Cuyper, I.M., Jongejan, A., Kat, M., van Stalborch, A.D., van Boxtel, A.L., Hubert, M., Geerts, D., van Buul, J.D., de Korte, D., Herzog, W., Margadant, C. (2021) The endosomal RIN2/Rab5C machinery prevents VEGFR2 degradation to control gene expression and tip cell identity during angiogenesis. Angiogenesis. 24(3):695-714
Ki, D.H., He, S., Rodig, S., Look, A.T. (2017) Overexpression of PDGFRA cooperates with loss of NF1 and p53 to accelerate the molecular pathogenesis of malignant peripheral nerve sheath tumors. Oncogene. 36(8):1058-1068
Landgraf, K., Schuster, S., Meusel, A., Garten, A., Riemer, T., Schleinitz, D., Kiess, W., Körner, A. (2017) Short-term overfeeding of zebrafish with normal or high-fat diet as a model for the development of metabolically healthy versus unhealthy obesity. BMC Physiology. 17:4
Lange, M., Ohnesorge, N., Hoffmann, D., Rocha, S.F., Benedito, R., Siekmann, A.F. (2022) Zebrafish mutants in vegfab can affect endothelial cell proliferation without altering ERK phosphorylation and are phenocopied by loss of PI3K signaling. Developmental Biology. 486:26-43
Lee, Y.S., Feng, C.W., Peng, M.Y., Chan, T.F., Chen, Y.C. (2021) Neuroprotective Effects of Estradiol plus Lithium Chloride via Anti-Apoptosis and Neurogenesis Pathway in
In Vitro
and
In Vivo
Parkinson's Disease Models. Parkinson's disease. 2021:3064892
Li, C., Ma, H., Wang, Y., Cao, Z., Graves-Deal, R., Powell, A.E., Starchenko, A., Ayers, G.D., Washington, M.K., Kamath, V., Desai, K., Gerdes, M.J., Solnica-Krezel, L., Coffey, R.J. (2014) Excess PLAC8 promotes an unconventional ERK2-dependent EMT in colon cancer. J. Clin. Invest.. 124(5):2172-87
Li, S., Dang, Y.Y., Che, G.O., Kwan, Y.W., Chan, S.W., Leung, G.P., Lee, S.M., Hoi, M.P. (2014) VEGFR tyrosine kinase inhibitor II (VRI) induced vascular insufficiency in zebrafish as a model for studying vascular toxicity and vascular preservation. Toxicology and applied pharmacology. 280(3):408-20
Lu, J.W., Yang, W.Y., Tsai, S.M., Lin, Y.M., Chang, P.H., Chen, J.R., Wang, H.D., Wu, J.L., Jin, S.L., and Yuh, C.H. (2013) Liver-Specific Expressions of HBx and src in the p53 Mutant Trigger Hepatocarcinogenesis in Zebrafish. PLoS One. 8(10):e76951
Mawed, S.A., He, Y., Zhang, J., Mei, J. (2020) Strategy of Hepatic Metabolic Defects Induced by
beclin1
Heterozygosity in Adult Zebrafish. International Journal of Molecular Sciences. 21(4):
Medishetti, R., Rani, R., Kavati, S., Mahilkar, A., Akella, V., Saxena, U., Kulkarni, P., Sevilimedu, A. (2020) A DNAzyme based knockdown model for Fragile-X syndrome in zebrafish reveals a critical window for therapeutic intervention. Journal of Pharmacological and Toxicological Methods. 101:106656
Mikdache, A., Boueid, M.J., van der Spek, L., Lesport, E., Delespierre, B., Loisel-Duwattez, J., Degerny, C., Tawk, M. (2021) Rgs4 is a regulator of mTOR activity required for motoneuron axon outgrowth and neuronal development in zebrafish. Scientific Reports. 11:13338
Nakagama, Y., Takeda, N., Ogawa, S., Takeda, H., Furutani, Y., Nakanishi, T., Sato, T., Hirata, Y., Oka, A., Inuzuka, R. (2019) Noonan syndrome-associated biallelic LZTR1 mutations cause cardiac hypertrophy and vascular malformations in zebrafish. Molecular genetics & genomic medicine. 8(3):e1107
Nakaya, N., Sultana, A., Tomarev, S.I. (2017) Impaired AMPA receptor trafficking by a double knockout of zebrafish olfactomedin1a/b. Journal of neurochemistry. 143(6):635-644
Oliveira, M.L., Veloso, A., Garcia, E.G., Iyer, S., Pereira, C., Barreto, V.M., Langenau, D.M., Barata, J.T. (2022) Mutant IL7R collaborates with MYC to induce T-cell acute lymphoblastic leukemia. Leukemia. 36(6):1533-1540
Qi, H., Schmöhl, F., Li, X., Qian, X., Tabler, C.T., Bennewitz, K., Sticht, C., Morgenstern, J., Fleming, T., Volk, N., Hausser, I., Heidenreich, E., Hell, R., Nawroth, P.P., Kroll, J. (2021) Reduced Acrolein Detoxification in akr1a1a Zebrafish Mutants Causes Impaired Insulin Receptor Signaling and Microvascular Alterations. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 8(18):e2101281
Ramirez, I.B., Pietka, G., Jones, D.R., Divecha, N., Aliam, A., Baraban, S.C., Hurlstone, A.F., and Lowe, M. (2012) Impaired Neural Development in a Zebrafish Model for Lowe Syndrome. Human molecular genetics. 21(8):1744-1759
Saera-Vila, A., Louie, K.W., Sha, C., Kelly, R.M., Kish, P.E., Kahana, A. (2018) Extraocular muscle regeneration in zebrafish requires late signals from Insulin-like growth factors. PLoS One. 13:e0192214
Santoriello, C., Deflorian, G., Pezzimenti, F., Kawakami, K., Lanfrancone, L., d'Adda di Fagagna, F., and Mione, M. (2009) Expression of H-RASV12 in a zebrafish model of Costello syndrome causes cellular senescence in adult proliferating cells. Disease models & mechanisms. 2(1-2):56-67
Santoriello, C., Gennaro, E., Anelli, V., Distel, M., Kelly, A., Köster, R.W., Hurlstone, A., and Mione, M. (2010) Kita Driven Expression of Oncogenic HRAS Leads to Early Onset and Highly Penetrant Melanoma in Zebrafish. PLoS One. 5(12):e15170
Sasore, T., Kennedy, B. (2014) Deciphering Combinations of PI3K/AKT/mTOR Pathway Drugs Augmenting Anti-Angiogenic Efficacy In Vivo. PLoS One. 9:e105280
Schenck, A., Goto-Silva, L., Collinet, C., Rhinn, M., Giner, A., Habermann, B., Brand, M., and Zerial, M. (2008) The endosomal protein Appl1 mediates Akt substrate specificity and cell survival in vertebrate development. Cell. 133(3):486-497
Seiliez, I., Médale, F., Aguirre, P., Larquier, M., Lanneretonne, L., Alami-Durante, H., Panserat, S., and Skiba-Cassy, S. (2013) Postprandial regulation of growth- and metabolism-related factors in zebrafish. Zebrafish. 10(2):237-248
Shi, C., Lu, Y., Zhai, G., Huang, J., Shang, G., Lou, Q., Li, D., Jin, X., He, J., Du, Z., Gui, J., Yin, Z. (2019) Hyperandrogenism in POMCa-deficient zebrafish enhances somatic growth without increasing adiposity. Journal of molecular cell biology. 12(4):291-304
Tsai, S.M., Liu, D.W., and Wang, W.P. (2013) Fibroblast growth factor (Fgf) signaling pathway regulates liver homeostasis in zebrafish. Transgenic Research. 22(2):301-314
Ulrich, F., Carretero-Ortega, J., Menéndez, J., Narvaez, C., Sun, B., Lancaster, E., Pershad, V., Trzaska, S., Véliz, E., Kamei, M., Prendergast, A., Kidd, K.R., Shaw, K.M., Castranova, D.A., Pham, V.N., Lo, B.D., Martin, B.L., Raible, D.W., Weinstein, B.M., Torres-Vazquez, J. (2016) Reck enables cerebrovascular development by promoting canonical Wnt signaling. Development (Cambridge, England). 143(1):147-59
Wang, K., Liu, C., Hou, Y., Zhou, H., Wang, X., Mai, K., He, G. (2019) Differential Apoptotic and Mitogenic Effects of Lectins in Zebrafish. Frontiers in endocrinology. 10:356
Wang, X., Li, J., Yang, Z., Wang, L., Li, L., Deng, W., Zhou, J., Wang, L., Xu, C., Chen, Q., Wang, Q.K. (2018) phlda3 overexpression impairs specification of hemangioblasts and vascular development. The FEBS journal. 285(21):4071-4081
Wu, X.M., Chen, W.Q., Hu, Y.W., Cao, L., Nie, P., Chang, M.X. (2018) RIP2 Is a Critical Regulator for NLRs Signaling and MHC Antigen Presentation but Not for MAPK and PI3K/Akt Pathways. Frontiers in immunology. 9:726
Xie, Y., Huang, D., Chu, L., Liu, Y., Sun, X., Li, J., Cheng, C.H.K. (2020) Igf3 is essential for ovary differentiation in zebrafish†. Biology of reproduction. 104(3):589-601
Yang, B.Y., Zhai, G., Gong, Y.L., Su, J.Z., Peng, X.Y., Shang, G.H., Han, D., Jin, J.Y., Liu, H.K., Du, Z.Y., Yin, Z., Xie, S.Q. (2017) Different physiological roles of insulin receptors in mediating nutrient metabolism in zebrafish. American journal of physiology. Endocrinology and metabolism. 315(1):E38-E51
Yang, J., Hartjes, K.A., Nelson, T.J., and Xu, X. (2014) Cessation of contraction induces cardiomyocyte remodeling during zebrafish cardiogenesis. American journal of physiology. Heart and circulatory physiology. 306(3):H382-H395
Yao, K., Ge, W. (2015) Differential regulation of Kit Ligand A (kitlga) expression in the zebrafish ovarian follicle cells - evidence for the existence of a cyclic adenosine 3', 5' monophosphate-mediated binary regulatory system during folliculogenesis. Molecular and Cellular Endocrinology. 402:21-31
Yao, K., Lau, S.W., and Ge, W. (2014) Differential Regulation of Kit Ligand A Expression in the Ovary by IGF-I via Different Pathways. Molecular endocrinology (Baltimore, Md.). 28(1):138-150
Zasu, A., Hishima, F., Thauvin, M., Yoneyama, Y., Kitani, Y., Hakuno, F., Volovitch, M., Takahashi, S.I., Vriz, S., Rampon, C., Kamei, H. (2022) NADPH-Oxidase Derived Hydrogen Peroxide and Irs2b Facilitate Re-oxygenation-Induced Catch-Up Growth in Zebrafish Embryo. Frontiers in endocrinology. 13:929668
Zeng, N., Bao, J., Shu, T., Shi, C., Zhai, G., Jin, X., He, J., Lou, Q., Yin, Z. (2022) Sexual dimorphic effects of
igf1
deficiency on metabolism in zebrafish. Frontiers in endocrinology. 13:879962
Zhang, Y., O'Leary, M.N., Peri, S., Wang, M., Zha, J., Melov, S., Kappes, D.J., Feng, Q., Rhodes, J., Amieux, P.S., Morris, D.R., Kennedy, B.K., Wiest, D.L. (2017) Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing. Cell Reports. 18:545-556
Additional Citations (1):
ZFIN Staff (2008) Antibody information from supplier. Manually curated data.
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