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Gene

dock6

ID
ZDB-GENE-120411-11
Name
dedicator of cytokinesis 6
Symbol
dock6 Nomenclature History
Previous Names
  • si:dkey-114l24.1
  • unm_sa1010
  • unm_sa899
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to act upstream of or within small GTPase mediated signal transduction. Human ortholog(s) of this gene implicated in Adams-Oliver syndrome. Orthologous to human DOCK6 (dedicator of cytokinesis 6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dock6 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Adams-Oliver syndrome Alliance Adams-Oliver syndrome 2 614219
Associated With dock6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR010703 Dedicator of cytokinesis, C-terminal
Domain IPR021816 Dedicator of cytokinesis C/D, N-terminal
Domain IPR027007 DHR-1 domain
Domain IPR027357 DHR-2 domain
Domain IPR037808 Dedicator of cytokinesis C, C2 domain
Family IPR026791 Dedicator of cytokinesis
Homologous_superfamily IPR035892 C2 domain superfamily
Homologous_superfamily IPR043161 Dedicator of cytokinesis, C-terminal, lobe A
Homologous_superfamily IPR043162 Dedicator of cytokinesis, C-terminal, lobe C
Domain Details Per Protein
Protein Length C2 domain superfamily Dedicator of cytokinesis Dedicator of cytokinesis C, C2 domain Dedicator of cytokinesis C/D, N-terminal Dedicator of cytokinesis, C-terminal Dedicator of cytokinesis, C-terminal, lobe A Dedicator of cytokinesis, C-terminal, lobe C DHR-1 domain DHR-2 domain
UniProtKB:F1Q4R1 2114
UniProtKB:Q502H2 146
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations