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Gene

myo18b

ID
ZDB-GENE-111111-8
Name
myosin XVIIIB
Symbol
myo18b Nomenclature History
Previous Names
  • fro
  • frozen (1)
  • schläfrig (1)
  • sig (1)
Type
protein_coding_gene
Location
Ambiguous Mapping Details/Browsers
Description
Predicted to enable ATP binding activity; actin binding activity; and cytoskeletal motor activity. Acts upstream of or within sarcomerogenesis. Predicted to be part of myosin complex. Is expressed in musculature system and somite border. Used to study myopathy.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
14 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With myo18b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Klippel-Feil syndrome 4 Alliance Klippel-Feil syndrome 4, autosomal recessive, with myopathy and facial dysmorphism 616549
Associated With myo18b Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR000048 IQ motif, EF-hand binding site
Domain IPR001609 Myosin head, motor domain
Domain IPR002928 Myosin tail
Family IPR028561 Unconventional myosin-XVIIIb
Homologous_superfamily IPR027401 Myosin IQ motif-containing domain superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036961 Kinesin motor domain superfamily
Domain Details Per Protein
Protein Length IQ motif, EF-hand binding site Kinesin motor domain superfamily Myosin head, motor domain Myosin IQ motif-containing domain superfamily Myosin tail P-loop containing nucleoside triphosphate hydrolase Unconventional myosin-XVIIIb
UniProtKB:A0A1W6S8R0 2103
UniProtKB:A0A1L3GW42 2100
Transcripts
Genome Browsers
No data available
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations