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Gene

dnaaf3

ID
ZDB-GENE-091204-296
Name
dynein axonemal assembly factor 3
Symbol
dnaaf3 Nomenclature History
Previous Names
  • PF22 (1)
  • si:dkey-224b4.3 (1)
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Involved in motile cilium assembly. Acts upstream of or within axonemal dynein complex assembly and cilium movement. Predicted to be located in dynein axonemal particle. Is expressed in floor plate spinal cord region; neuromast; peripheral olfactory organ; and pronephros. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 2. Orthologous to human DNAAF3 (dynein axonemal assembly factor 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Mitchison et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dnaaf3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
primary ciliary dyskinesia 2 Alliance Ciliary dyskinesia, primary, 2 606763
Associated With dnaaf3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR027974 Domain of unknown function DUF4470
Domain IPR028235 Dynein assembly factor 3, C-terminal domain
Family IPR039304 Dynein assembly factor 3, axonemal
Domain Details Per Protein
Protein Length Domain of unknown function DUF4470 Dynein assembly factor 3, axonemal Dynein assembly factor 3, C-terminal domain
UniProtKB:F1Q7Z7
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations