Gene

chn2

ID
ZDB-GENE-091020-5
Name
chimerin 2
Symbol
chn2 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to enable GTPase activator activity. Predicted to be involved in regulation of GTPase activity. Predicted to act upstream of or within intracellular signal transduction; positive regulation of GTPase activity; and regulation of small GTPase mediated signal transduction. Orthologous to human CHN2 (chimerin 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With chn2 Human Ortholog
No data available
Associated With chn2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000198 Rho GTPase-activating protein domain
Domain IPR000980 SH2 domain
Domain IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Domain IPR020454 Diacylglycerol/phorbol-ester binding
Domain IPR035840 Chimaerin, SH2 domain
Domain IPR037860 Chimaerin, RhoGAP domain
Family IPR017356 Chimaerin
Homologous_superfamily IPR008936 Rho GTPase activation protein
Homologous_superfamily IPR036860 SH2 domain superfamily
Domain Details Per Protein
Protein Length Chimaerin Chimaerin, RhoGAP domain Chimaerin, SH2 domain Diacylglycerol/phorbol-ester binding Protein kinase C-like, phorbol ester/diacylglycerol-binding domain Rho GTPase-activating protein domain Rho GTPase activation protein SH2 domain SH2 domain superfamily
UniProtKB:F1QT22 450
UniProtKB:E7F3K5 466
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations