Gene

prkd1

ID
ZDB-GENE-080131-1
Name
protein kinase D1
Symbol
prkd1 Nomenclature History
Previous Names
  • PKD1 (1)
  • si:dkeyp-47g2.1
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to enable ATP binding activity; calcium-dependent protein kinase C activity; and metal ion binding activity. Acts upstream of or within regulation of angiogenesis and regulation of lymphangiogenesis. Predicted to be located in cytoplasm and membrane. Orthologous to human PRKD1 (protein kinase D1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Hollenbach et al., 2013
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Hollenbach et al., 2013
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prkd1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Congenital heart defects and ectodermal dysplasia 617364
Associated With prkd1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Domain IPR020454 Diacylglycerol/phorbol-ester binding
Family IPR015727 Protein kinase C mu-related
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR011993 PH-like domain superfamily
Domain Details Per Protein
Protein Length Diacylglycerol/phorbol-ester binding PH-like domain superfamily Pleckstrin homology domain Protein kinase, ATP binding site Protein kinase C-like, phorbol ester/diacylglycerol-binding domain Protein kinase C mu-related Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:X1WHC7 886
UniProtKB:E7FA73 878
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-prkd1 polyclonal Rabbit
Santa Cruz Biotechnology, Inc.
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations