Gene

dapk1

ID
ZDB-GENE-060526-177
Name
death-associated protein kinase 1
Symbol
dapk1 Nomenclature History
Previous Names
  • si:ch211-66i11.1
  • wu:fj09c03
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and positive regulation of apoptotic process. Predicted to act upstream of or within apoptotic process; protein phosphorylation; and signal transduction. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in urinary bladder cancer. Orthologous to human DAPK1 (death associated protein kinase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Zhou et al., 2020
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dapk1 Human Ortholog
No data available
Associated With dapk1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000488 Death domain
Domain IPR000719 Protein kinase domain
Domain IPR020683 Ankyrin repeat-containing domain
Domain IPR020859 Roc domain
Family IPR020676 Death-associated protein kinase 1
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR011029 Death-like domain superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036770 Ankyrin repeat-containing domain superfamily
Repeat IPR002110 Ankyrin repeat
Domain Details Per Protein
Protein Length Ankyrin repeat Ankyrin repeat-containing domain Ankyrin repeat-containing domain superfamily Death-associated protein kinase 1 Death domain Death-like domain superfamily P-loop containing nucleoside triphosphate hydrolase Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Roc domain Serine/threonine-protein kinase, active site
UniProtKB:A0A2R8QS56 1477
UniProtKB:A5WVL9 1439
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations