Gene

pvrl2l

ID
ZDB-GENE-060503-249
Name
PVR cell adhesion molecule related 2 like
Symbol
pvrl2l Nomenclature History
Previous Names
  • si:dkey-225e11.1
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to be involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in adherens junction. Is expressed in cardiovascular system; epidermis; nervous system; and neural plate. Human ortholog(s) of this gene implicated in Alzheimer's disease and multiple sclerosis. Orthologous to human PVR (PVR cell adhesion molecule) and NECTIN2 (nectin cell adhesion molecule 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from Thisse et al., 2008
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pvrl2l Human Ortholog
No data available
Associated With pvrl2l Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003599 Immunoglobulin subtype
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013106 Immunoglobulin V-set domain
Domain IPR013162 CD80-like, immunoglobulin C2-set
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Length CD80-like, immunoglobulin C2-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype Immunoglobulin V-set domain
UniProtKB:F1R7U2 267
UniProtKB:B0CLW6 328
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations