Gene

iqcb1

ID
ZDB-GENE-041212-47
Name
IQ motif containing B1
Symbol
iqcb1 Nomenclature History
Previous Names
  • nphp5 (1)
  • zgc:101792
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have calmodulin binding activity. Involved in opsin transport and pronephros development. Human ortholog(s) of this gene implicated in Leber congenital amaurosis; Senior-Loken syndrome; nephronophthisis; and retinitis pigmentosa 3. Orthologous to human IQCB1 (IQ motif containing B1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With iqcb1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Senior-Loken syndrome Alliance Senior-Loken syndrome 5 609254
Associated With iqcb1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR000048 IQ motif, EF-hand binding site
Family IPR028765 IQ calmodulin-binding motif-containing protein 1
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length IQ calmodulin-binding motif-containing protein 1 IQ motif, EF-hand binding site P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A8KC58 295
UniProtKB:A0A0R4IC62 464
UniProtKB:F1QYF8 586
UniProtKB:A0A0G2KKU5 421
UniProtKB:Q5PRA5 595
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations