|ZFIN ID: ZDB-PUB-991020-7|
Differential expression of Tbx4 and Tbx5 in zebrafish fin buds
Tamura, K., Yonei-Tamura, S., and Belmonte, J.C.
|Source:||Mechanisms of Development 87(1-2): 181-184 (Journal)|
|Registered Authors:||Izpisúa Belmonte, Juan Carlos|
|Keywords:||T-box; Tbx4; Tbx5; zebrafish; gene expression; embryogenesis; fin bud|
|PubMed:||10495283 Full text @ Mech. Dev.|
Tamura, K., Yonei-Tamura, S., and Belmonte, J.C. (1999) Differential expression of Tbx4 and Tbx5 in zebrafish fin buds. Mechanisms of Development. 87(1-2):181-184.
ABSTRACTIn here we report the identification of two new members of the T-box gene family, zf-tbx5 and zf-tbx4, from the Zebrafish, Danio rerio. The amino acid sequences within the T-box domain share high homology with the mouse, chick, and newt orthologs. Whole mount in situ hybridization revealed specific expression of these genes in the eye and Fin buds. zf-tbx5 expression is restricted to the pectoral Fin bud, whilst zf-tbx4 transcripts are confined in the pelvic Fin bud. These results reveal the conserved expression pattern of Tbx5 and Tbx4 during appendage development in all animal species studied to date.
- Genes / Markers (2)