ZFIN ID: ZDB-PUB-990427-16
Spatially and temporally-restricted expression of two T-box genes during zebrafish embryogenesis
Yonei-Tamura, S., Tamura, K., Tsukui, T., and Izpisúa Belmonte, J.C.
Date: 1999
Source: Mechanisms of Development   80(2): 219-221 (Journal)
Registered Authors: Izpisúa Belmonte, Juan Carlos
Keywords: T-box; zebrafish; gene expression; Tbr1; Tbx3; embryogenesis
MeSH Terms:
  • Amino Acid Sequence
  • Animals
  • DNA-Binding Proteins/biosynthesis
  • DNA-Binding Proteins/genetics*
  • Embryo, Nonmammalian/metabolism
  • Gene Expression Regulation, Developmental*
  • Humans
  • Mice
  • Molecular Sequence Data
  • Organ Specificity
  • Sequence Alignment
  • Sequence Homology, Amino Acid
  • Species Specificity
  • T-Box Domain Proteins*
  • Transcription Factors/biosynthesis
  • Transcription Factors/genetics*
  • Xenopus
  • Xenopus Proteins*
  • Zebrafish/embryology
  • Zebrafish/genetics*
  • Zebrafish Proteins*
PubMed: 10072792 Full text @ Mech. Dev.
T-box genes are conserved in all animal species. We have identified two members of the T-box gene family from the zebrafish, Danio rerio. Zf-tbr1 and zf-tbx3 share high amino acid identity with human, murine, chick and Xenopus orthologs and are expressed in specific regions during zebrafish development.